Validation of the orthoiodosupplementation program:
A Rebuttal of Dr. Gaby’s Editorial on iodine
By: Guy E. Abraham, M.D. and David Brownstein, M.D.
Orthoiodosupplementation is the daily amount of the essential element iodine needed for whole body sufficiency 1 . Whole body sufficiency for iodine is assessed by an iodine/iodide loading test. The test consists of ingesting 4 tablets of a solid dosage form of Lugol (Iodoral®), containing a total of 50 mg iodine/iodide. Then urinary iodide levels are measured in the following 24 hr collection. The iodine/iodide loading test is based on the concept that the normally functioning human body has a mechanism to retain ingested iodine until whole body sufficiency for iodine is achieved. For consistency and uniformity, the same solid dosage form of Lugol (Iodoral®) is used in the loading test and for orthoiodosupplementation. During orthoiodosupplementation, a negative feedback mechanism is triggered that progressively adjusts the excretion of iodine to balance the intake. As the body iodine content increases, the percent of the iodine load retained decreases with a concomitant increase in the amount of iodide excreted in the 24 hr urine collection. When whole body sufficiency for iodine is achieved, the absorbed iodine/iodide is quantitatively excreted as iodide in the urine. At such time, 90% or more of the iodine load is recovered in the 24 hr urine collection, and the body retains approximately 1.5 gm of elemental iodine.
In the August/September 2005 issue of Townsend Letter, Dr. Allen Gaby, M.D. wrote an Editorial on iodine, questioning the validity of the iodine/iodide loading test we use to assess whole body sufficiency for iodine; and the safety and efficacy of the orthoiodosupplementation program in medical practice. Our rebuttal will cover four topics:
1. The safe and effective use of iodine by our medical predecessors.
2. The computation of the average daily intake of iodide from seaweed by mainland Japanese.
3. The validation of the iodine/iodide loading test.
4. The effectiveness and safety of orthoiodosupplementation in current medical practice.
Read it here: A Rebuttal to Dr Gaby’s Editorial on Iodine.